MaFem
MaFem is a brand name for a misoprostol medication, which is a synthetic prostaglandin. It contains Misoprostol 200 mcg.
Primary uses:
- Prevention and treatment of bleeding which occurs immediately after childbirth (postpartum haemorrhage)
- Used for the induction of labour (IOL)
- Treatment of incomplete abortion and silent miscarriage in the first trimester
- Can be used to heal existing ulcers
- May help prevent ulcers in the stomach and intestine.
Mechanism of action:
- Misoprostol is a synthetic prostaglandin E1 analog that stimulates prostaglandin E1 receptors on parietal cells in the stomach to reduce gastric acid secretion.
- Mucus and bicarbonate secretion are also increased along with thickening of the mucosal bilayer so the mucosa can generate new cells.
- Misoprostol binds to smooth muscle cells in the uterine lining to increase the strength and frequency of contractions as well as degrade collagen and reduce cervical tone
Mode of administration:
- Induction of labour (IOL): Dissolve 200mcg in 200ml of water and take 25ml of that solution equivalent to 25mcg misoprostol as a single dose. Take each next dose after two hours until labour starts.
- Treatment of incomplete abortion and silent miscarriage in the first trimester – Administered 800mcg and repeated after 24 hours.
Ghana (Head Office):
Hs# C327, 14 Nii Boney Street, Dzorwulu – Accra
Tel: (+233) 302 772 799
Liberia:
Bushrod Island, Sayon Town, Monsterrado Country, Monrovia
Tel: (+231) 778 172 882
Sierra Leone:
13B Mandingo Town, off Main Motor Road, Congo Cross, Freetown.
Tel: (+232) 30 145 438